IL-21 and TGF-β are required for differentiation of human TH17 cells-Reference-Cited by-同舟云学术

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IL-21 and TGF-β are required for differentiation of human TH17 cells

Published:2008-07-01 Issue:7202 Volume:454 Page:350-352
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Yang Li,Anderson David E.,Baecher-Allan Clare,Hastings William D.,Bettelli Estelle,Oukka Mohamed,Kuchroo Vijay K.,Hafler David A.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature07021.pdf

Reference14 articles.

1. Kikly, K., Liu, L., Na, S. & Sedgwick, J. D. The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation. Curr. Opin. Immunol. 18, 670–675 (2006)

2. Wilson, N. J. et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nature Immunol. 8, 950–957 (2007)

3. Bettelli, E. et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441, 235–238 (2006)

4. Mangan, P. R. et al. Transforming growth factor-β induces development of the TH17 lineage. Nature 441, 231–234 (2006)

5. Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M. & Stockinger, B. TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24, 179–189 (2006)

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