Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis-Reference-Cited by-同舟云学术

Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis

Published:2009-05-31 Issue:6 Volume:15 Page:626-632
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Krishnamoorthy Gurumoorthy,Saxena Amit,Mars Lennart T,Domingues Helena S,Mentele Reinhard,Ben-Nun Avraham,Lassmann Hans,Dornmair Klaus,Kurschus Florian C,Liblau Roland S,Wekerle Hartmut

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.1975.pdf

Reference23 articles.

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2. Wekerle, H. Breaking ignorance: the case of the brain. in Current Concepts in Autoimmunity and Chronic Inflammation (eds. Radbruch, A. & Lipsky, P.E.) 25–50 (Springer, Berlin, 2006).

3. Bettelli, E. et al. Myelin oligodendrocyte glycoprotein–specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. J. Exp. Med. 197, 1073–1081 (2003).

4. Litzenburger, T. et al. B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice. J. Exp. Med. 188, 169–180 (1998).

5. Delarasse, C. et al. Myelin/oligodendrocyte glycoprotein–deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice. J. Clin. Invest. 112, 544–553 (2003).

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