Significant pharmacokinetic differences of berberine are attributable to variations in gut microbiota between Africans and Chinese
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep27671.pdf
Reference25 articles.
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2. Menees, S., Saad, R. & Chey, W. D. Agents that act luminally to treat diarrhoea and constipation. Nat Rev Gastroenterol Hepatol 9, 661–74 (2012).
3. Kong, W. et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med 10, 1344–51 (2004).
4. Zhang, Y. et al. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab 93, 2559–65 (2008).
5. Zhang, Z. et al. Berberine activates thermogenesis in white and brown adipose tissue. Nat Commun 5, 5493 (2014).
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