Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential-Reference-Cited by-同舟云学术

Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

Published:2011-09 Issue:1 Volume:2 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Stapleton Nigel M.,Andersen Jan Terje,Stemerding Annette M.,Bjarnarson Stefania P.,Verheul Ruurd C.,Gerritsen Jacoline,Zhao Yixian,Kleijer Marion,Sandlie Inger,de Haas Masja,Jonsdottir Ingileif,van der Schoot C. Ellen,Vidarsson Gestur

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms1608.pdf

Reference53 articles.

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2. Salfeld, J. G. Isotype selection in antibody engineering. Nat. Biotechnol. 25, 1369–1372 (2007).

3. Natsume, A. et al. Engineered antibodies of IgG1/IgG3 mixed isotype with enhanced cytotoxic activities. Cancer Res. 68, 3863–3872 (2008).

4. Jefferis, R. Antibody therapeutics: isotype and glycoform selection. Expert Opin. Biol. Ther. 7, 1401–1413 (2007).

5. Morell, A., Terry, W. D. & Waldmann, T. A. Metabolic properties of IgG subclasses in man. J. Clin. Invest. 49, 673–680 (1970).

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