Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis-Reference-Cited by-同舟云学术

Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis

Published:2017-07-14 Issue:1 Volume:8 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Aguilo Nacho,Gonzalo-Asensio Jesus^ORCID,Alvarez-Arguedas Samuel,Marinova Dessislava,Gomez Ana Belen,Uranga Santiago,Spallek Ralf,Singh Mahavir,Audran Regine,Spertini François,Martin Carlos^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms16085.pdf

Reference47 articles.

1. Marinova, D., Gonzalo-Asensio, J., Aguilo, N. & Martin, C. Recent developments in tuberculosis vaccines. Expert Rev. Vaccines 12, 1431–1448 (2013).

2. WHO. Global tuberculosis report 2016. http://www.who.int/tb/publications/global_report/en/ (2016).

3. Fine, P. E. Variation in protection by BCG: implications of and for heterologous immunity. Lancet 346, 1339–1345 (1995).

4. Brosch, R. et al. Genome plasticity of BCG and impact on vaccine efficacy. Proc. Natl Acad. Sci. USA 104, 5596–5601 (2007).

5. Pym, A. S., Brodin, P., Brosch, R., Huerre, M. & Cole, S. T. Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti. Mol. Microbiol. 46, 709–717 (2002).

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