Functional switching
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/ni.3607.pdf
Reference5 articles.
1. Wang, A.C. et al. Evidence for control of synthesis of the variable regions of the heavy chains of immunoglobulins G and M by the same gene. Proc. Natl Acad. Sci. USA 66, 337–343 (1970)
2. Davis, M.M. et al. An immunoglobulin heavy-chain gene is formed by at least two recombinational events. Nature 283, 733–739 (1980)
3. Snapper, C.M. & Paul, W.E. Interferon-γ and B cell stimulating factor-1 reciprocally regulate Ig isotype production. Science 236, 944–947 (1987)
4. Muramatsu, M. et al. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potent RNA editing enzyme. Cell 102, 553–563 (2000).
5. Xu, Z. et al. Immunoglobulin class-switch DNA recombination: induction, targeting and beyond. Nat. Rev. Immunol. 12, 517–531 (2012).
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