Understanding the interplay between the proteasome pathway and autophagy in response to dual PI3K/mTOR inhibition in myeloma cells is essential for their effective clinical application-Reference-Cited by-同舟云学术

Understanding the interplay between the proteasome pathway and autophagy in response to dual PI3K/mTOR inhibition in myeloma cells is essential for their effective clinical application

Published:2013-05-14 Issue:12 Volume:27 Page:2397-2403
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Aronson L I,Davenport E L,Mirabella F^ORCID,Morgan G J,Davies F E

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/leu2013150.pdf

Reference14 articles.

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2. Davenport EL, Moore HE, Dunlop AS, Sharp SY, Workman P, Morgan GJ et al. Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells. Blood 2007; 110: 2641–2649.

3. Hoang B, Benavides A, Shi Y, Frost P, Lichtenstein A . Effect of autophagy on multiple myeloma cell viability. Mol Cancer Ther 2009; 8: 1974–1984.

4. Iwata A, Riley BE, Johnston JA, Kopito RR . HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. J Biol Chem 2005; 280: 40282–40292.

5. Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441: 885–889.

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