Abstract
AbstractIn environments characterized by extended multi-stress conditions, pathogens develop a variety of immune escape mechanisms to enhance their ability to infect the host. The capsules, polymers that bacteria secrete near their cell wall, participates in numerous bacterial life processes and plays a crucial role in resisting host immune attacks and adapting to their niche. Here, we discuss the relationship between capsules and bacterial virulence, summarizing the molecular mechanisms of capsular regulation and pathogenesis to provide new insights into the research on the pathogenesis of pathogenic bacteria.
Publisher
Springer Science and Business Media LLC
Reference211 articles.
1. Rajagopal, M. & Walker, S. Envelope structures of gram-positive bacteria. Curr. Top. Microbiol. Immunol. 404, 1–44 (2017).
2. Feng, Y. et al. Attenuation of Streptococcus suis virulence by the alteration of bacterial surface architecture. Sci. Rep. 2, 710 (2012).
3. Moayeri, M. et al. Anthrax pathogenesis. Annu Rev. Microbiol 69, 185–208 (2015).
4. Tomcsik, J. & Baumann-Grace, J. B. Polysaccharide capsule of Bacillus megaterium. Proc. Soc. Exp. Biol. Med. Soc. Exp. Biol. Med. 101, 570–571 (1959).
5. Dochez, A. R. & Avery, O. T. The elaboration of specific soluble substance by pneumococcus during growth. J. Exp. Med. 26, 477–493 (1917).
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献