A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation-Reference-Cited by-同舟云学术

A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation

Published:2015-08-27 Issue:1 Volume:5 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Kleikers Pamela WM.,Hooijmans Carlijn,Göb Eva,Langhauser Friederike,Rewell Sarah SJ.,Radermacher Kim,Ritskes-Hoitinga Merel,Howells David W.,Kleinschnitz Christoph,HHW Schmidt Harald

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep13428.pdf

Reference73 articles.

1. Prinz, F., Schlange, T. & Asadullah, K. Believe it or not: how much can we rely on published data on potential drug targets? Nat Rev Drug Discov 10, 712–712 (2011).

2. Anonymous. Facilitating reproducibility. Nat. Chem. Biol. 9, 345–345 (2013).

3. Ioannidis, J. P. A. Why most published research findings are false. PLoS Med. 2, e124 (2005).

4. Mullard, A. Reliability of ‘new drug target’ claims called into question. Nat Rev Drug Discov 10, 643–644 (2011).

5. Arrowsmith, J. Trial watch: Phase II failures: 2008–2010. Nat Rev Drug Discov 10, 328–329 (2011).

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