In search of an anti-inflammatory drug for Alzheimer disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Neurology (clinical)
Link
http://www.nature.com/articles/s41582-019-0307-9.pdf
Reference10 articles.
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2. Lambert, J. C. et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer’s disease. Nat. Genet. 41, 1094–1099 (2009).
3. Jonsson, T. et al. Variant of TREM2 associated with the risk of Alzheimer’s disease. N. Engl. J. Med. 368, 107–116 (2013).
4. Wilkins, H. M. et al. Mitochondrial lysates induce inflammation and Alzheimer’s disease-relevant changes in microglial and neuronal cells. J. Alzheimers Dis. 45, 305–318 (2015).
5. Howard, R. et al. Minocycline at 2 different dosages versus placebo for patients with mild Alzheimer disease: a randomized clinical trial. JAMA Neurol. https://doi.org/10.1001/jamaneurol.2019.3762 (2019).
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