Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/ncomms14015.pdf
Reference70 articles.
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4. Allsopp, R. C. & Harley, C. B. Evidence for a critical telomere length in senescent human fibroblasts. Exp. Cell Res. 219, 130–136 (1995).
5. Hemann, M. T., Strong, M. A., Hao, L. Y. & Greider, C. W. The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107, 67–77 (2001).
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