Reduced interleukin‐2 responsiveness impairs the ability of T reg cells to compete for IL‐2 in nonobese diabetic mice
Author:
Affiliation:
1. The University of Queensland Diamantina Institute, University of Queensland, Translational Research Institute Brisbane Queensland Australia
Funder
National Health and Medical Research Council
Juvenile Diabetes Research Foundation United Kingdom
Publisher
Wiley
Subject
Cell Biology,Immunology,Immunology and Allergy
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1038/icb.2016.7
Reference45 articles.
1. Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
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4. CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis
5. Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients
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