The Anti-α4β7 Integrin Therapeutic Antibody for Inflammatory Bowel Disease, Vedolizumab, Ameliorates Eosinophilic Esophagitis: a Novel Clinical Observation
Author:
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Gastroenterology,Hepatology
Link
http://www.nature.com/articles/s41395-018-0145-1.pdf
Reference5 articles.
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2. The binding specificity and selective antagonism of vedolizumab, an anti-47 integrin therapeutic antibody in development for inflammatory bowel diseases.;Soler;J Pharmacol Exp Ther,2009
3. Integrin 47 mediates human eosinophil interaction with MAdCAM-1, VCAM-1 and fibronectin.;Walsh;Immunology,1996
4. Engagement of 47 integrins by monoclonal antibodies or ligands enhances survival of human eosinophils in vitro.;Meerschaert;J Immunol,1999
5. The 47-integrin is dynamically expressed on murine eosinophils and involved in eosinophil trafficking to the intestine.;Brandt;Clin Exp Allergy,2006
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