MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12-Reference-Cited by-同舟云学术

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MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12

Published:2018-09 Issue:9 Volume:9 Page:
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Lian Wei-Shiung,Ko Jih-Yang,Wu Re-Weng,Sun Yi-Chih,Chen Yu-Shan,Wu Shin-Long,Weng Lin-Hsiu,Jahr Holger,Wang Feng-Sheng

Funder

National Health Research Institutes (NHRI)

Chang Gung Medical Foundation

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/s41419-018-0994-y.pdf

Reference54 articles.

1. Glyn-Jones, S. et al. Osteoarthritis. Lancet 386, 376–387 (2015).

2. Chen, D. et al. Osteoarthritis: toward a comprehensive understanding of pathological mechanism. Bone Res. 5, 16044 (2017).

3. Kim, J. H. et al. Regulation of the catabolic cascade in osteoarthritis by the zinc-ZIP8-MTF1 axis. Cell 156, 730–743 (2014).

4. Lambert, C. et al. Gene expression pattern of cells from inflamed and normal areas of osteoarthritis synovial membrane. Arthritis Rheumatol. 66, 960–968 (2014).

5. Zhen, G. et al. Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis. Nat. Med. 19, 704–712 (2013).

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