Fructose fuels lung adenocarcinoma through GLUT5
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology
Link
http://www.nature.com/articles/s41419-018-0630-x.pdf
Reference15 articles.
1. Tappy, L. & Le, K. A. Metabolic effects of fructose and the worldwide increase in obesity. Physiol. Rev. 90, 23–46 (2010).
2. Hannou, S. A. et al. Fructose metabolism and metabolic disease. J. Clin. Invest. 128, 545–555 (2018).
3. Jiang, Y. et al. A sucrose-enriched diet promotes tumorigenesis in mammary gland in part through the 12-lipoxygenase pathway. Cancer Res. 76, 24–29 (2016).
4. Liu, H. et al. Fructose induces transketolase flux to promote pancreatic cancer growth. Cancer Res. 70, 6368–6376 (2010).
5. Chen, W. L. et al. Enhanced fructose utilization mediated by SLC2A5 is a unique metabolic feature of acute myeloid leukemia with therapeutic potential. Cancer Cell. 30, 779–791 (2016).
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