A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma-Reference-Cited by-同舟云学术

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A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma

Published:2018-07 Issue:7 Volume:9 Page:
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Yao Zhi-qiang,Zhang Xin,Zhen Yongqi,He Xu-Ying,Zhao Shuangmei,Li Xi-Feng,Yang Bo,Gao Feng,Guo Fu-You,Fu Leilei,Liu Xian-Zhi,Duan Chuan-Zhi

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/s41419-018-0799-z.pdf

Reference42 articles.

1. Smith, J. S. et al. A phylogenetically conserved NAD+−dependent protein deacetylase activity in the Sir2 protein family. Proc. Natl. Acad. Sci. USA 97, 6658–6663 (2009).

2. Araki, T., Sasaki, Y. & Milbrandt, J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305, 1010–1013 (2004).

3. Lee, I. H. et al. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc. Natl. Acad. Sci. USA 105, 3374–3379 (2008).

4. Sakamoto, J., Miura, T., Shimamoto, K. & Horio, Y. Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain. FEBS Lett. 556, 281–286 (2004).

5. Ramadori, G. et al. SIRT1: anatomical distribution and regulation by energy availability. J. Neurosci. 28, 9989–9996 (2008).

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