Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage-Reference-Cited by-同舟云学术

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Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage

Published:2018-11 Issue:11 Volume:9 Page:
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Bae Yun-Hee,Joo Hyejin,Bae Jinhyun,Hyeon Seung Jae,Her Song,Ko Eunhwa,Choi Hwan Geun,Ryu Hoon,Hur Eun-Mi,Bu Youngmin,Lee Byoung Dae

Funder

National Research Foundation

Korea Institute of Science and Technology

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/s41419-018-1180-y.pdf

Reference62 articles.

1. Biskup, S. et al. Localization of LRRK2 to membranous and vesicular structures in mammalian brain. Ann. Neurol. 60, 557–569 (2006).

2. Han, B. S. et al. Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra. Neurosci. Lett. 442, 190–194 (2008).

3. Zimprich, A. et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 44, 601–607 (2004).

4. Di Fonzo, A. et al. A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson’s disease. Lancet 365, 412–415 (2005).

5. Gilks, W. P. et al. A common LRRK2 mutation in idiopathic Parkinson’s disease. Lancet 365, 415–416 (2005).

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4. Pharmacological Inhibition of LRRK2 Exhibits Neuroprotective Activity in Mouse Photothrombotic Stroke Model;Experimental Neurobiology;2024-02-29

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