A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor
Author:
Funder
Cancer Research UK
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology
Link
http://www.nature.com/articles/s41419-018-1115-7.pdf
Reference48 articles.
1. Vale, C. L. et al. Addition of docetaxel or bisphosphonates to standard of care in men with localised or metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data. Lancet Oncol. 17, 243–256 (2016).
2. Markert, E. K., Mizuno, H., Vazquez, A. & Levine, A. J. Molecular classification of prostate cancer using curated expression signatures. Proc. Natl Acad. Sci. USA 108, 21276–21281 (2011).
3. Sboner, A. et al. Molecular sampling of prostate cancer: a dilemma for predicting disease progression. BMC. Med. Genom. 3, 8 (2010).
4. Taylor, B. S. et al. Integrative genomic profiling of human prostate cancer. Cancer Cell. 18, 11–22 (2010).
5. Cancer Genome Atlas Research, N. The molecular taxonomy of primary prostate. Cancer Cell. 163, 1011–1025 (2015).
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