A new signaling cascade linking BMP4, BMPR1A, ΔNp73 and NANOG impacts on stem-like human cell properties and patient outcome
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology
Link
http://www.nature.com/articles/s41419-018-1042-7.pdf
Reference55 articles.
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2. Zhou, H. S., Carter, B. Z. & Andreeff, M. Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia: Yin and Yang. Cancer Biol. Med. 13, 248–259 (2016).
3. Shafat, M. S. et al. Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment. Blood 129, 1320–1332 (2017).
4. Toofan, P. & Wheadon, H. Role of the bone morphogenic protein pathway in developmental haemopoiesis and leukaemogenesis. Biochem. Soc. Trans. 44, 1455–1463 (2016).
5. Kirmizitas, A., Meiklejohn, S., Ciau-Uitz, A., Stephenson, R. & Patient, R. Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage. Proc. Natl Acad. Sci. USA 114, 5814–5821 (2017).
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