The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein–Barr virus by inhibiting the molecular chaperone function of Hsp70-Reference-Cited by-同舟云学术

The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein–Barr virus by inhibiting the molecular chaperone function of Hsp70

Published:2018-06-29 Issue:7 Volume:9 Page:
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Wang Huan^ORCID,Bu Lang,Wang Chao,Zhang Yaqian,Zhou Heng,Zhang Xi,Guo Wei,Long Cong,Guo Deyin,Sun Xiaoping

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/s41419-018-0779-3.pdf

Reference59 articles.

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2. Sun, X. et al. Hsp90 inhibitors block outgrowth of EBV-infected malignant cells in vitro and in vivo through an EBNA1-dependent mechanism. Proc. Natl. Acad. Sci. USA 107, 3146–3151 (2010).

3. Whitehurst, C. B. et al. Knockout of Epstein–Barr virus BPLF1 retards B-cell transformation and lymphoma formation in humanized mice. mBio. 6, e01574-01515 (2015).

4. Raab-Traub, N. Epstein–Barr virus and nasopharyngeal carcinoma. Semin. Cancer Biol. 3, 297–307 (1992).

5. Wang, F. Z. et al. Maribavir inhibits Epstein–Barr virus transcription in addition to viral DNA replication. J. Virol. 83, 12108–12117 (2009).

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