New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease

Author:

Kleymann Gerald,Fischer Rüdiger,Betz Ulrich A.K.,Hendrix Martin,Bender Wolfgang,Schneider Udo,Handke Gabriele,Eckenberg Peter,Hewlett Guy,Pevzner Veniamin,Baumeister Judith,Weber Olaf,Henninger Kerstin,Keldenich Jörg,Jensen Axel,Kolb Jörg,Bach Ute,Popp Andreas,Mäben Jutta,Frappa Isabelle,Haebich Dieter,Lockhoff Oswald,Rübsamen-Waigmann Helga

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference16 articles.

1. Knipe, D.M. & Howley, P.M. Fields Virology, 4th edn. 2399–2509 (Lippincott Williams Wilkins, Philadelphia, 2001).

2. Boehmer, P.E. & Lehmann I.R. Herpes simplex virus replication. Ann. Rev. Biochem. 66, 347–384 (1997).

3. Schaeffer, H.J. et al. 9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes group. Nature 272, 583–585 (1978).

4. Keating, M.R. Antiviral agents for non-human immunodeficiency virus infection. Mayo Clin. Proc. 74, 1266–1283 (1999).

5. Fischer, R. et al. Thiazole urea derivatives and their utilization as antiviral agents. Patent application WO-00/53591-A, PCT/EP01498 EP1161423 (2000).

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