Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/ncomms15363.pdf
Reference63 articles.
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2. Krieg, A. M. Therapeutic potential of Toll-like receptor 9 activation. Nat. Rev. Drug Discov. 5, 471–484 (2006).
3. Klinman, D. M. Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat. Rev. Immunol. 4, 249–258 (2004).
4. Ohto, U. et al. Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9. Nature 520, 702–705 (2015).
5. Pohar, J., Kužnik Krajnik, A., Jerala, R. & Benčina, M. Minimal sequence requirements for oligodeoxyribonucleotides activating human TLR9. J. Immunol. 194, 3901–3908 (2015).
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