Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens-Reference-Cited by-同舟云学术

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

Published:2017-05-05 Issue:1 Volume:8 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Morgens David W.,Wainberg Michael,Boyle Evan A.^ORCID,Ursu Oana,Araya Carlos L.,Tsui C. Kimberly,Haney Michael S.,Hess Gaelen T.,Han Kyuho^ORCID,Jeng Edwin E.,Li Amy,Snyder Michael P.,Greenleaf William J.,Kundaje Anshul^ORCID,Bassik Michael C.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms15178.pdf

Reference58 articles.

1. Shalem, O., Sanjana, N. E. & Zhang, F. High-throughput functional genomics using CRISPR-Cas9. Nat. Rev. Genet. 16, 299–311 (2015).

2. Wang, T., Wei, J. J., Sabatini, D. M. & Lander, E. S. Genetic screens in human cells using the CRISPR-Cas9 system. Science 343, 80–84 (2014).

3. Shalem, O. et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 343, 84–87 (2014).

4. Koike-Yusa, H., Li, Y., Tan, E.-P., Velasco-Herrera, M. D. C. & Yusa, K. Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library. Nat. Biotechnol. 32, 267–273 (2014).

5. Zhou, Y. et al. High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells. Nature 509, 487–491 (2014).

Cited by 301 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular programs guiding arealization of descending cortical pathways;Nature;2024-09-11

2. Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells;Biochemical Pharmacology;2024-09

3. Development of a quinic acid-induced CRISPR/Cas9 genome editing system and its application for the activation of ilicicolin H biosynthesis in Trichoderma reesei;International Journal of Biological Macromolecules;2024-09

4. Genome-Wide Screening Approaches for Biochemical Reactions Independent of Cell Growth;Annual Review of Genomics and Human Genetics;2024-08-27

5. Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes;2024-08-20