Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/ncomms15700.pdf
Reference61 articles.
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3. Ngo, T. et al. Identifying ligands at orphan GPCRs: current status using structure-based approaches. Br. J. Pharmacol. 173, 2934–2951 (2016).
4. Wise, A., Jupe, S. C. & Rees, S. The identification of ligands at orphan G-protein coupled receptors. Annu. Rev. Pharmacol. Toxicol. 44, 43–66 (2004).
5. Insel, P. A., Tang, C. M., Hahntow, I. & Michel, M. C. Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targets. Biochim. Biophys. Acta 1768, 994–1005 (2007).
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