Loss of Asxl2 leads to myeloid malignancies in mice-Reference-Cited by-同舟云学术

Loss of Asxl2 leads to myeloid malignancies in mice

Published:2017-06-08 Issue:1 Volume:8 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Li Jianping,He Fuhong^ORCID,Zhang Peng,Chen Shi,Shi Hui,Sun Yanling,Guo Ying,Yang Hui,Man Na,Greenblatt Sarah,Li Zhaomin,Guo Zhengyu,Zhou Yuan,Wang Lan,Morey Lluis,Williams Sion,Chen Xi,Wang Qun-Tian,Nimer Stephen D.,Yu Peng,Wang Qian-Fei,Xu Mingjiang,Yang Feng-Chun

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms15456.pdf

Reference42 articles.

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3. Fisher, C. L., Randazzo, F., Humphries, R. K. & Brock, H. W. Characterization of Asxl1, a murine homolog of additional sex combs, and analysis of the Asx-like gene family. Gene 369, 109–118 (2006).

4. Cao, R. et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298, 1039–1043 (2002).

5. Abdel-Wahab, O. et al. ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. Cancer Cell 22, 180–193 (2012).

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