Myelodysplastic syndrome with t(6;9)(p22;q34.1)/DEK-NUP214 better classified as acute myeloid leukemia? A multicenter study of 107 cases

Author:

Fang HongORCID,Yabe Mariko,Zhang Xiaohui,Kim YoungORCID,Wu Xiaojun,Wei PengORCID,Chi Sunyi,Zheng Lan,Garcia-Manero GuillermoORCID,Shao Lina,Yuan Ji,Shen Yulei,Zheng GangORCID,Tang Guiling,Wang Wei,Loghavi SanamORCID,Shen Qi,Yuan Yongzhong,He RongORCID,Chen Dong,Medeiros L. JeffreyORCID,Hu ShiminORCID

Publisher

Springer Science and Business Media LLC

Subject

Pathology and Forensic Medicine

Reference31 articles.

1. Slovak ML, Gundacker H, Bloomfield CD, Dewald G, Appelbaum FR, Larson RA, et al. A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare ‘poor prognosis’ myeloid malignancies. Leukemia. 2006;20:1295–7.

2. Arber DA, Brunning RD, Le Beau MM, Falini B, Vardiman JW, Porwit A, et al. Acute myeloid leukaemia with t(6;9)(p23;q34.1); DEK-NUP214. In: Swerdlow S, Campo E, Harris N, Jaffe E, Pileri S, Stein H, et al., editors. WHO classification of tumours of haematopoietic and lymphoid tissues. Revised 4th ed. Lyon: IARC; 2017. p. 137–8.

3. Arber DA, Brunning RD, Le Beau MM, Falini B, Vardiman JW, Porwit A, et al. Acute myeloid laeukemia with t(6;9)(p23;q34); DEK-NUP214. In: Swerdlow S, Campo E, Harris N, Jaffe E, Pileri S, Stein H, et al., editors. WHO classification of tumours of haematopietic and lymphoid tissues. 4th ed. Lyon: IARC; 2008. p. 115–6.

4. Rowley JD, Potter D. Chromosomal banding patterns in acute nonlymphocytic leukemia. Blood. 1976;47:705–21.

5. Boer J, Bonten-Surtel J, Grosveld G. Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis. Mol Cell Biol. 1998;18:1236–47.

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