Two phase 3, multicenter, randomized, placebo-controlled clinical trials of fampridine-SR for treatment of spasticity in chronic spinal cord injury-Reference-Cited by-同舟云学术

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Two phase 3, multicenter, randomized, placebo-controlled clinical trials of fampridine-SR for treatment of spasticity in chronic spinal cord injury

Published:2013-11-12 Issue:1 Volume:52 Page:70-76
ISSN:1362-4393
Container-title:Spinal Cord
language:en
Short-container-title:Spinal Cord

Author:

Cardenas D D,Ditunno J F,Graziani V,McLain A B,Lammertse D P,Potter P J,Alexander M S,Cohen R,Blight A R

Publisher

Springer Science and Business Media LLC

Subject

Clinical Neurology,Neurology,General Medicine

Link

http://www.nature.com/articles/sc2013137.pdf

Reference20 articles.

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2. Shi R, Blight AR . Differential effects of low and high concentrations of 4-aminopyridine on axonal conduction in normal and injured spinal cord. Neuroscience 1997; 77: 553–562.

3. Coetzee WA, Amarillo Y, Chiu J, Chow A, Lau D, McCormack T et al. Molecular diversity of K+ channels. Ann NY Acad Sci 1999; 868: 233–285.

4. Vollmer T, Blight AR, Henney HR . Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained release 10-mg tablets in patients with multiple sclerosis: a 2-week, open-label, follow-up study. Clin Ther 2009; 31: 2215–2223.

5. Renganathan M, Sidach S, Blight AR . Effects of 4-aminopyridine on cloned hERG channels expressed in mammalian cells. Arch Drug Info 2009; 2: 51–57.

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