Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers

Author:

Adar Y,Stark M,Bram E E,Nowak-Sliwinska P,van den Bergh H,Szewczyk G,Sarna T,Skladanowski A,Griffioen A W,Assaraf Y G

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Reference33 articles.

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2. Kusnierczyk H, Cholody WM, Paradziej-Lukowicz J, Radzikowski C, Konopa J . Experimental antitumor activity and toxicity of the selected triazolo- and imidazoacridinones. Arch Immunol Ther Exp (Warsz) 1994; 42: 415–423.

3. Dziegielewski J, Slusarski B, Konitz A, Skladanowski A, Konopa J . Intercalation of imidazoacridinones to DNA and its relevance to cytotoxic and antitumor activity. Biochem Pharmacol 2002; 63: 1653–1662.

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5. Haimeur A, Conseil G, Deeley RG, Cole SP . The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity and regulation. Curr Drug Metab 2004; 5: 21–53.

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