Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology
Link
http://www.nature.com/articles/cddis2017487.pdf
Reference63 articles.
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2. Krojer T, Sawa J, Huber R, Clausen T . HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues. Nat Struct Mol Biol 2010; 17: 844–852.
3. Martins LM, Iaccarino I, Tenev T, Gschmeissner S, Totty NF, Lemoine NR et al. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J Biol Chem 2002; 277: 439–444.
4. Figaj D, Gieldon A, Bartczak M, Koper T, Zarzecka U, Lesner A et al. The LD loop as an important structural element required for transmission of the allosteric signal in the HtrA (DegP) protease from Escherichia coli. FEBS J 2016; 283: 3471–3487.
5. Singh N, Kuppili RR, Bose K . The structural basis of mode of activation and functional diversity: a case study with HtrA family of serine proteases. Arch Biochem Biophys 2011; 516: 85–96.
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