High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy-Reference-Cited by-同舟云学术

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High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy

Published:2014-05 Issue:5 Volume:5 Page:e1203-e1203
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Rossi M,Rotblat B,Ansell K,Amelio I,Caraglia M,Misso G,Bernassola F,Cavasotto C N,Knight R A,Ciechanover A,Melino G

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/cddis2014113.pdf

Reference60 articles.

1. Ciechanover A . Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting. Cell Death Differ 2005; 12: 1178–1190.

2. Hershko A . The ubiquitin system for protein degradation and some of its roles in the control of the cell division cycle. Cell Death Differ 2005; 12: 1191–1197.

3. Melino G . Discovery of the ubiquitin proteasome system and its involvement in apoptosis. Cell Death Differ 2005; 12: 1155–1157.

4. Ciechanover A . The ubiquitin-proteasome proteolytic pathway. Cell 1994; 79: 13–21.

5. Pickart CM . Mechanisms underlying ubiquitination. Annu Rev Biochem 2001; 70: 503–533.

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