Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedback-Reference-Cited by-同舟云学术

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Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedback

Published:2016-04 Issue:4 Volume:7 Page:e2197-e2197
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Wilson K,Auer M,Binnie M,Zheng X,Pham N T,Iredale J P,Webster S P,Mole D J

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/cddis201687.pdf

Reference22 articles.

1. Mole DJ, McFerran NV, Collett G, O'Neill C, Diamond T, Garden OJ et al. Tryptophan catabolites in mesenteric lymph may contribute to pancreatitis-associated organ failure. Br J Surg 2008; 95: 855–867.

2. Mole DJ, Webster S, Uings I, Zheng X, Binnie M, Wilson K et al. Kynurenine–3–monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis. Nat Med 2016; 22: 202–209.

3. Giorgini F, Guidetti P, Nguyen Q, Bennett SC, Muchowski PJ . A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease. Nat Genet 2005; 37: 526–531.

4. Moffett JR, Namboodiri MA . Tryptophan and the immune response. Immunol Cell Biol 2003; 81: 247–265.

5. Stone TW, Behan WM, MacDonald M, Darlington LG . Possible mediation of quinolinic acid-induced hippocampal damage by reactive oxygen species. Amino Acids 2000; 19: 275–281.

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1. Kynurenine 3-monooxygenase limits de novo NAD⁺ synthesis through dietary tryptophan in renal proximal tubule epithelial cell models;American Journal of Physiology-Cell Physiology;2024-05-01

2. Kynurenine monooxygenase regulates inflammation during critical illness and recovery in experimental acute pancreatitis;Cell Reports;2023-08

3. Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane;Biomedicines;2022-09-15

4. The Kynurenine Pathway as a Potential Target for Neuropathic Pain Therapy Design: From Basic Research to Clinical Perspectives;International Journal of Molecular Sciences;2021-10-13

5. Assessment of the safety, pharmacokinetics and pharmacodynamics of GSK3335065, an inhibitor of kynurenine monooxygenase, in a randomised placebo‐controlled first‐in‐human study in healthy volunteers;British Journal of Clinical Pharmacology;2021-08-22

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