Mitochondrial dysfunction in an Opa1Q285STOP mouse model of dominant optic atrophy results from Opa1 haploinsufficiency-Reference-Cited by-同舟云学术

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Mitochondrial dysfunction in an Opa1Q285STOP mouse model of dominant optic atrophy results from Opa1 haploinsufficiency

Published:2016-07 Issue:7 Volume:7 Page:e2309-e2309
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Kushnareva Y,Seong Y,Andreyev A Y,Kuwana T,Kiosses W B,Votruba M,Newmeyer D D

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/cddis2016160.pdf

Reference50 articles.

1. Lenaers G, Reynier P, Elachouri G, Soukkarieh C, Olichon A, Belenguer P et al. OPA1 functions in mitochondria and dysfunctions in optic nerve. Int J Biochem Cell Biol 2009; 41: 1866–1874.

2. Lee YJ, Jeong SY, Karbowski M, Smith CL, Youle RJ . Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol Biol Cell 2004; 15: 5001–5011.

3. Olichon A, Baricault L, Gas N, Guillou E, Valette A, Belenguer P et al. Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J Biol Chem 2003; 278: 7743–7746.

4. Kushnareva YE, Gerencser AA, Bossy B, Ju WK, White AD, Waggoner J et al. Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity. Cell Death Differ 2013; 20: 353–365.

5. Cogliati S, Frezza C, Soriano ME, Varanita T, Quintana-Cabrera R, Corrado M et al. Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency. Cell 2013; 155: 160–171.

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