Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences

Author:

Yu Yue,Katiyar Shashank P,Sundar Durai,Kaul Zeenia,Miyako Eijiro,Zhang Zhenya,Kaul Sunil C,Reddel Roger RORCID,Wadhwa Renu

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Reference55 articles.

1. Cerni C . Telomeres, telomerase, and myc. An update. Mutat Res 2000; 462: 31–47.

2. Deng Y, Chan SS, Chang S . Telomere dysfunction and tumour suppression: the senescence connection. Nat Rev Cancer 2008; 8: 450–458.

3. Reddel RR, Bryan TM, Murnane JP . Immortalized cells with no detectable telomerase activity. A review. Biochemistry (Mosc) 1997; 62: 1254–1262.

4. Yeager TR, Neumann AA, Englezou A, Huschtscha LI, Noble JR, Reddel RR . Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res 1999; 59: 4175–4179.

5. Cesare AJ, Reddel RR . Alternative lengthening of telomeres: models, mechanisms and implications. Nat Rev Genet 2010; 11: 319–330.

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