MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL-Reference-Cited by-同舟云学术

MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL

Published:2016-08 Issue:8 Volume:7 Page:e2345-e2345
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Vikström Ingela B,Slomp Anne,Carrington Emma M,Moesbergen Laura M,Chang Catherine,Kelly Gemma L,Glaser Stefan P,Jansen J H Marco,Leusen Jeanette H W,Strasser Andreas,Huang David C S,Lew Andrew M,Peperzak Victor,Tarlinton David M

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/cddis2016237.pdf

Reference35 articles.

1. Czabotar PE, Lessene G, Strasser A, Adams JM . Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy. Nat Rev Mol Cell Biol 2014; 15: 49–63.

2. Brunner C, Marinkovic D, Klein J, Samardzic T, Nitschke L, Wirth T . B cell-specific transgenic expression of Bcl2 rescues early B lymphopoiesis but not B cell responses in BOB.1/OBF.1-deficient mice. J Exp Med 2003; 197: 1205–1211.

3. Grillot DA, Merino R, Pena JC, Fanslow WC, Finkelman FD, Thompson CB et al. Bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. J Exp Med 1996; 183: 381–391.

4. Campbell KJ, Bath ML, Turner ML, Vandenberg CJ, Bouillet P, Metcalf D et al. Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance. Blood 2010; 116: 3197–3207.

5. Chattopadhyay G, Khan AQ, Sen G, Colino J, DuBois W, Rubtsov A et al. Transgenic expression of Bcl-xL or Bcl-2 by murine B cells enhances the in vivo antipolysaccharide, but not antiprotein, response to intact Streptococcus pneumonia. J Immunol 2007; 179: 7523–7534.

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