Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation

Author:

Datan E,Roy S G,Germain G,Zali N,McLean J E,Golshan G,Harbajan S,Lockshin R A,Zakeri ZORCID

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Reference73 articles.

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2. Guha-Sapir D, Schimmer B . Dengue fever: new paradigms for a changing epidemiology. Emerg Themes Epidemiol 2005; 2: 1.

3. Avirutnan P, Malasit P, Seliger B, Bhakdi S, Husmann M . Dengue virus infection of human endothelial cells leads to chemokine production, complement activation, and apoptosis. J Immunol 1998; 161: 6338–6346.

4. McLean JE, Wudzinska A, Datan E, Quaglino D, Zakeri Z . Flavivirus NS4A-induced autophagy protects cells against death and enhances virus replication. J Biol Chem 2011; 286: 22147–22159.

5. Lee YR, Lei HY, Liu MT, Wang JR, Chen SH, Jiang-Shieh YF et al. Autophagic machinery activated by dengue virus enhances virus replication. Virology 2008; 374: 240–248.

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