Transcription regulation by the Mediator complex
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm.2017.115.pdf
Reference147 articles.
1. Lee, T. I. & Young, R. A. Transcription of eukaryotic protein-coding genes. Annu. Rev. Genet. 34, 77–137 (2000).
2. Malik, S. & Roeder, R. G. Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells. Trends Biochem. Sci. 25, 277–283 (2000).
3. Myers, L. C. & Kornberg, R. D. Mediator of transcriptional regulation. Annu. Rev. Biochem. 69, 729–749 (2000).
4. Holstege, F. C. et al. Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95, 717–728 (1998).
5. Soutourina, J., Wydau, S., Ambroise, Y., Boschiero, C. & Werner, M. Direct interaction of RNA polymerase II and mediator required for transcription in vivo. Science 331, 1451–1454 (2011). This study provides in vivo evidence that a direct interaction between Pol II and Mediator is generally required for Pol II recruitment and transcription in yeast.
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