The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder
Author:
Funder
Janssen Pharmaceuticals
Publisher
Springer Science and Business Media LLC
Subject
Biological Psychiatry,Cellular and Molecular Neuroscience,Psychiatry and Mental health
Link
http://www.nature.com/articles/s41398-019-0553-z.pdf
Reference50 articles.
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3. Hatzinger, M., Hemmeter, U. M., Baumann, K., Brand, S. & Holsboer-Trachsler, E. The combined DEX-CRH test in treatment course and long-term outcome of major depression. J. Psychiatr. Res. 36, 287–297 (2002).
4. Hatzinger, M., Hemmeter, U. M., Brand, S., Ising, M. & Holsboer-Trachsler, E. Electroencephalographic sleep profiles in treatment course and long-term outcome of major depression: association with DEX/CRH-test response. J. Psychiatr. Res. 38, 453–465 (2004).
5. Bao, A.-M., Meynen, G. & Swaab, D. The stress system in depression and neurodegeneration: focus on the human hypothalamus. Brain Res. Rev. 57, 531–553 (2008).
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