NK3R antagonists: a novel approach for menopause symptoms
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
https://www.nature.com/articles/s41574-023-00891-8.pdf
Reference10 articles.
1. Davis, S. R. et al. Menopause. Nat. Rev. Dis. Primers 1, 15004 (2015).
2. Nelson, H. D. Menopause. Lancet 371, 760–770 (2008).
3. Conklin, M. & Santoro, N. Neurokinin receptor antagonists as potential non-hormonal treatments for vasomotor symptoms of menopause. Ther. Adv. Reprod. Health 17, 26334941231177611 (2023).
4. Mittelman-Smith, M. A., Krajewski-Hall, S. J., McMullen, N. T. & Rance, N. E. Neurokinin 3 receptor-expressing neurons in the median preoptic nucleus modulate heat-dissipation effectors in the female rat. Endocrinology 156, 2552–2562 (2015).
5. Rance, N. E., Dacks, P. A., Mittelman-Smith, M. A., Romanovsky, A. A. & Krajewski-Hall, S. J. Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: a novel hypothesis on the mechanism of hot flushes. Front. Neuroendocrinol. 34, 211–227 (2013).
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