Does lower limb amputation concern all SGLT2 inhibitors?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
http://www.nature.com/articles/s41574-018-0001-9.pdf
Reference10 articles.
1. Li, D. et al. Risks of diabetic foot syndrome and amputation associated with sodium glucose co-transporter 2 inhibitors: a meta-analysis of randomized controlled trials. Diabetes Metab. https://doi.org/10.1016/j.diabet.2018.02.001 (2018).
2. Neal, B. et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N. Engl. J. Med. 377, 644–657 (2017).
3. Khouri, C., Cracowski, J. L. & Roustit, M. SGLT-2 inhibitors and the risk of lower-limb amputation: is this a class effect? Diabetes Obes. Metab. https://doi.org/10.1111/dom.13255 (2018).
4. Inzucchi, S. E. et al. Empagliflozin and assessment of lower-limb amputations in the EMPA-REG OUTCOME trial. Diabetes Care 41, e4–e5 (2018).
5. Monami, M. et al. Toe amputations with SGLT-2 inhibitors: data from randomized clinical trials. Acta Diabetol. 54, 411–413 (2017).
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1. Safety of sodium‐glucose co‐transporter‐2 inhibitors on amputation across categories of baseline cardiovascular disease and diuretics use in patients with type 2 diabetes;Diabetes, Obesity and Metabolism;2023-07-28
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