Skeletal disorders associated with the growth hormone–insulin-like growth factor 1 axis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
https://www.nature.com/articles/s41574-022-00649-8.pdf
Reference165 articles.
1. Giustina, A., Mazziotti, G. & Canalis, E. Growth hormone, insulin-like growth factors, and the skeleton. Endocr. Rev. 29, 535–559 (2008).
2. Mazziotti, G., Frara, S. & Giustina, A. Pituitary diseases and bone. Endocr. Rev. 39, 440–488 (2018).
3. Schorr, M. & Miller, K. K. The endocrine manifestations of anorexia nervosa: mechanisms and management. Nat. Rev. Endocrinol. 13, 174–186 (2017).
4. Canalis, E., Centrella, M., Burch, W. & McCarthy, T. L. Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures. J. Clin. Invest. 83, 60–65 (1989). The seminal study shows that IGF1 mediates the skeletal effects of PTH.
5. Miyakoshi, N., Kasukawa, Y., Linkhart, T. A., Baylink, D. J. & Mohan, S. Evidence that anabolic effects of PTH on bone require IGF-I in growing mice. Endocrinology 142, 4349–4356 (2001).
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