IL4I1-driven AHR signature: a new avenue for cancer therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics
Link
http://www.nature.com/articles/s41392-021-00529-z.pdf
Reference5 articles.
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2. Murray, I. A., Patterson, A. D. & Perdew, G. H. Aryl hydrocarbon receptor ligands in cancer: friend and foe. Nat. Rev. Cancer 14, 801–814 (2014).
3. Cervenka, I., Agudelo, L. Z. & Ruas, J. L. Kynurenines: tryptophanas metabolites in exercise, inflammation, and mental health. Science 357, eaaf9794 (2017).
4. Boulland, M. L. et al. Human IL4I1 is a secreted L-phenylalanine oxidase expressed by mature dendritic cells that inhibits T-lymphocyte proliferation. Blood 110, 220–227 (2007).
5. Hofbauer, J. P. et al. Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL. Leukemia 25, 1452–1458 (2011).
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