Structure of human NCC: insights into the inhibition mechanism of thiazides-Reference-Cited by-同舟云学术

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Structure of human NCC: insights into the inhibition mechanism of thiazides

Published:2023-07-03 Issue:1 Volume:8 Page:
ISSN:2059-3635
Container-title:Signal Transduction and Targeted Therapy
language:en
Short-container-title:Sig Transduct Target Ther

Author:

de Souza Goncalves Livia,Yottasan Pattareeya,Cil Onur

Funder

Cystic Fibrosis Foundation

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics

Link

https://www.nature.com/articles/s41392-023-01527-z.pdf

Reference5 articles.

1. Fan, M., Zhang, J., Lee, C. J., Zhang, J. & Feng, L. Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. Nature 614, 788–793 (2023).

2. Subramanya, A. R. & Ellison, D. H. Distal convoluted tubule. Clin. J. Am. Soc. Nephrol. 9, 2147–2163 (2014).

3. Cil, O. et al. Small-molecule inhibitors of pendrin potentiate the diuretic action of furosemide. J. Am. Soc. Nephrol. 27, 3706–3714 (2016).

4. Ernst, M. E. & Fravel, M. A. Thiazide and the thiazide-like diuretics: review of hydrochlorothiazide, chlorthalidone, and indapamide. Am. J. Hypertens. 35, 573–586 (2022).

5. Kucharczyk, P. et al. Thiazides attenuate insulin secretion through inhibition of mitochondrial carbonic anhydrase 5b in beta-islet cells in mice. J. Am. Soc. Nephrol. https://pubmed.ncbi.nlm.nih.gov/36927842/ (2023).

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