HIF-1α and HDAC1 mediated regulation of FAM99A-miR92a signaling contributes to hypoxia induced HCC metastasis
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics
Link
http://www.nature.com/articles/s41392-020-00223-6.pdf
Reference5 articles.
1. Chen, Z. L. et al. microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin. J. Biol. Chem.286, 10725–10734 (2011).
2. Deng, S. J. et al. Hypoxia-induced LncRNA-BX111 promotes metastasis and progression of pancreatic cancer through regulating ZEB1 transcription. Oncogene37, 5811–5828 (2018).
3. Li, X. et al. Hypoxia-induced lncRNA-NUTF2P3-001 contributes to tumorigenesis of pancreatic cancer by derepressing the miR-3923/KRAS pathway. Oncotarget7, 6000–6014 (2016).
4. Liu, Q. et al. Hypoxia induces genomic DNA demethylation through the activation of HIF-1alpha and transcriptional upregulation of MAT2A in hepatoma cells. Mol. Cancer Therapeutics10, 1113–1123 (2011).
5. Zhang, G. et al. MicroRNA-92a functions as an oncogene in colorectal cancer by targeting PTEN. Digestive Dis. Sci.59, 98–107 (2014).
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