Opioid receptors: single molecule studies shed light on mechanisms of efficacy
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Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41392-024-01920-2.pdf
Reference5 articles.
1. Zhao, J. et al. Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629, 474–480 (2024).
2. Hauser, A. S. et al. Common coupling map advances GPCR-G protein selectivity. Elife 11, e74107 (2022).
3. Rosenbaum, D. M. et al. Structure and function of an irreversible agonist-b2 adrenoceptor complex. Nature 469, 236–240 (2011).
4. Lamichhane, R. et al. Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR. Proc. Natl. Acad. Sci. USA 112, 14254–14259 (2015).
5. Gregorio, G. G. et al. Single-molecule analysis of ligand efficacy in β2AR-protein activation. Nature 547, 68–73 (2017).
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