ALYREF mediates RNA m5C modification to promote hepatocellular carcinoma progression
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics
Link
https://www.nature.com/articles/s41392-023-01395-7.pdf
Reference5 articles.
1. Forner, A., Reig, M. & Bruix, J. Hepatocellular carcinoma. Lancet 391, 1301–1314 (2018).
2. Barbieri, I. & Kouzarides, T. Role of RNA modifications in cancer. Nat. Rev. Cancer 20, 303–322 (2020).
3. Park, I. Y. et al. Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Gastroenterology 132, 1476–1494 (2007).
4. Yang, X. et al. 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader. Cell Res. 27, 606–625 (2017).
5. Xue, C., Zhao, Y., Li, G. & Li, L. Multi-Omic analyses of the m5C regulator ALYREF reveal its essential roles in hepatocellular carcinoma. Front. Oncol. 11, 633415 (2021).
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