PD-L1 regulates genomic stability via interaction with cohesin-SA1 in the nucleus
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics
Link
http://www.nature.com/articles/s41392-021-00463-0.pdf
Reference5 articles.
1. Ribas, A. & Wolchok, J. D. Cancer immunotherapy using checkpoint blockade. Science 359, 1350–1355 (2018).
2. Chang, C. H. et al. Metabolic competition in the tumor microenvironment is a driver of cancer progression. Cell 162, 1229–1241 (2015).
3. Remeseiro, S. et al. Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres. EMBO J. 31, 2076–2089 (2012).
4. Yu, J. et al. Regulation of sister chromatid cohesion by nuclear PD-L1. Cell Res. 3, 590–601 (2020).
5. Gao, Yang et al. Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy. Nat. Cell Biol. 22, 1064–1075 (2020).
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