Overcoming unintended immunogenicity in immunocompetent mouse models of metastasis: the case of GFP
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics
Link
https://www.nature.com/articles/s41392-022-00929-9.pdf
Reference5 articles.
1. Grzelak, C. A. et al. Elimination of fluorescent protein immunogenicity permits modeling of metastasis in immune-competent settings. Cancer Cell 40,1–2 (2022). https://doi.org/10.1016/j.ccell.2021.11.004. Epub 2021 Dec 2.
2. Lambert, A. W., Pattabiraman, D. R. & Weinberg, R. A. Emerging biological principles of metastasis. Cell 168, 670–691 (2017).
3. Giacobbe, A. & Abate-Shen, C. Modeling metastasis in mice: a closer look. Trends Cancer 7, 916–929 (2021).
4. Day, C. P. et al. “Glowing head” mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts. PLoS ONE 9, e109956 (2014).
5. Ferdosi, S. R. et al. Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes. Nat. Commun. 10, 1842 (2019).
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