High stearic acid diet modulates gut microbiota and aggravates acute graft-versus-host disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics
Link
http://www.nature.com/articles/s41392-021-00600-9.pdf
Reference5 articles.
1. Wu, X. et al. Prediction of acute GVHD and relapse by metabolic biomarkers after allogeneic hematopoietic stem cell transplantation. JCI Insight. 3, e99672 (2018).
2. Tomas, J. et al. High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine. Proc. Natl. Acad. Sci. USA. 113, E5934–E5943 (2016).
3. Shono, Y. et al. Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice. Sci. Transl. Med. 8, 339ra371 (2016).
4. Ansaldo, E. et al. Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasis. Science 364, 1179–1184 (2019).
5. Fujiwara, H. et al. Microbial metabolite sensor GPR43 controls severity of experimental GVHD. Nat. Commun. 9, 3674 (2018).
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