Structure of the full-length glucagon class B G-protein-coupled receptor-Reference-Cited by-同舟云学术

Structure of the full-length glucagon class B G-protein-coupled receptor

Published:2017-05-17 Issue:7657 Volume:546 Page:259-264
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Zhang Haonan,Qiao Anna,Yang Dehua,Yang Linlin,Dai Antao,de Graaf Chris,Reedtz-Runge Steffen,Dharmarajan Venkatasubramanian,Zhang Hui,Han Gye Won,Grant Thomas D.,Sierra Raymond G.,Weierstall Uwe,Nelson Garrett,Liu Wei,Wu Yanhong,Ma Limin,Cai Xiaoqing,Lin Guangyao,Wu Xiaoai,Geng Zhi,Dong Yuhui,Song Gaojie,Griffin Patrick R.,Lau Jesper,Cherezov Vadim,Yang Huaiyu,Hanson Michael A.,Stevens Raymond C.,Zhao Qiang,Jiang Hualiang,Wang Ming-Wei,Wu Beili

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature22363.pdf

Reference44 articles.

1. Lagerström, M. C. & Schiöth, H. B. Structural diversity of G protein-coupled receptors and significance for drug discovery. Nat. Rev. Drug Discov. 7, 339–357 (2008)

2. Hollenstein, K. et al. Insights into the structure of class B GPCRs. Trends Pharmacol. Sci. 35, 12–22 (2014)

3. Finan, B. et al. Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic impact for metabolic disease. Cell 167, 843–857.e14 (2016)

4. Longuet, C. et al. The glucagon receptor is required for the adaptive metabolic response to fasting. Cell Metab. 8, 359–371 (2008)

5. Parthier, C., Reedtz-Runge, S., Rudolph, R. & Stubbs, M. T. Passing the baton in class B GPCRs: peptide hormone activation via helix induction? Trends Biochem. Sci. 34, 303–310 (2009)

Cited by 181 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Innovative Strategies in X-ray Crystallography for Exploring Structural Dynamics and Reaction Mechanisms in Metabolic Disorders;Journal of Personalized Medicine;2024-08-27

2. The Inferential Binding Sites of GCGR for Small Molecules Using Protein Dynamic Conformations and Crystal Structures;International Journal of Molecular Sciences;2024-08-01

3. Altered desensitization and internalization patterns of rodent versus human glucose‐dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge;British Journal of Pharmacology;2024-07

4. Glucagon does not directly stimulate pituitary secretion of ACTH, GH or copeptin;Peptides;2024-06

5. Impact of secretin receptor homo-dimerization on natural ligand binding;Nature Communications;2024-05-23