CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells-Reference-Cited by-同舟云学术

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

Published:2017-05-24 Issue:7656 Volume:546 Page:168-172
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Kim Jiyeon,Hu Zeping,Cai Ling,Li Kailong,Choi Eunhee,Faubert Brandon,Bezwada Divya,Rodriguez-Canales Jaime,Villalobos Pamela,Lin Yu-Fen,Ni Min,Huffman Kenneth E.,Girard Luc,Byers Lauren A.,Unsal-Kacmaz Keziban,Peña Christopher G.,Heymach John V.,Wauters Els,Vansteenkiste Johan,Castrillon Diego H.,Chen Benjamin P. C.,Wistuba Ignacio,Lambrechts Diether,Xu Jian,Minna John D.,DeBerardinis Ralph J.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature22359.pdf

Reference30 articles.

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2. Ji, H. et al. LKB1 modulates lung cancer differentiation and metastasis. Nature 448, 807–810 (2007)

3. Liu, Y. et al. Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer. Cancer Discov. 3, 870–879 (2013)

4. Kim, H. S. et al. Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer. Cell 155, 552–566 (2013)

5. Liu, H., Dong, H., Robertson, K. & Liu, C. DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma. Am. J. Pathol. 178, 652–661 (2011)

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